Journals Information
International Journal of Cardiovascular and Cerebrovascular Disease(CEASE PUBLICATION) Vol. 2(2), pp. 18 - 27
DOI: 10.13189/ijccd.2014.020202
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New Estimation Method of Total Creatine Phosphokinase Release in Early Stage in Acute Myocardial Infarction
Tomoki Kitawaki 1,*, Hisao Oka 1, Shinichi Usui 1, Satoshi Hirohata 2, Shozo Kusachi 1
1 Department of Medical Technology, Okayama University Graduate School of Health Sciences, 2-5-1 Shikata, Kita-ku, Okayama, Japan
2 Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata, Kita-ku, Okayama, Japan
ABSTRACT
In this paper, we introduce a new estimation method for total creatine phosphokinase release based on a physiological model of the serum creatine phosphokinase (CPK) activity change that can be used to estimate the total CPK release accurately, as early as possible, without frequent blood sampling. The physiological model and a new calculation method were applied to the serum CPK activity change of patients who suffered acute myocardial infarction (AMI). According to the results, the physiological model showed good agreement with the serum CPK activity change and the estimated value of the total CPK release also agreed well with that calculated using the conventional technique with clinically acceptable accuracy.
KEYWORDS
CPK Activity Change, Acute Myocardial Infarction, Physiological Model, Logistic Function
Cite This Paper in IEEE or APA Citation Styles
(a). IEEE Format:
[1] Tomoki Kitawaki , Hisao Oka , Shinichi Usui , Satoshi Hirohata , Shozo Kusachi , "New Estimation Method of Total Creatine Phosphokinase Release in Early Stage in Acute Myocardial Infarction," International Journal of Cardiovascular and Cerebrovascular Disease(CEASE PUBLICATION), Vol. 2, No. 2, pp. 18 - 27, 2014. DOI: 10.13189/ijccd.2014.020202.
(b). APA Format:
Tomoki Kitawaki , Hisao Oka , Shinichi Usui , Satoshi Hirohata , Shozo Kusachi (2014). New Estimation Method of Total Creatine Phosphokinase Release in Early Stage in Acute Myocardial Infarction. International Journal of Cardiovascular and Cerebrovascular Disease(CEASE PUBLICATION), 2(2), 18 - 27. DOI: 10.13189/ijccd.2014.020202.