Journals Information
Advances in Pharmacology and Pharmacy Vol. 13(4), pp. 662 - 673
DOI: 10.13189/app.2025.130416
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Zebra Fish: A Prospective Experimental Model
Riya K. Mehta 1,*, Yash D. Dudhwala 2, Nandini M. Gamit 1, Vipul G. Gajera 3, Ketan V. Shah 2
1 Shree Naranjibhai Lalbhai Patel College of Pharmacy, Umrakh, Gujarat, India
2 Department of Pharmaceutics, Shree Naranjibhai Lalbhai Patel College of Pharmacy, Umrakh, Gujarat, India
3 Department of Pharmacology, Shree Naranjibhai Lalbhai Patel College of Pharmacy, Umrakh, Gujarat, India
ABSTRACT
Clinical trials for novel pharmaceuticals are expensive in terms of both financial costs and human health when unexpected human safety problems occur. Through preclinical safety testing, the drug development industry tries to reduce these occurrences. Many medical studies use animal models to learn more about the causes of animal and human diseases, as well as to develop new treatment measure. The zebrafish (Danio rerio) exhibits a variety of traits that make it a useful model for research on human genetics and illness. The zebrafish is a useful experimental model for behavioural, genetic, and toxicological research that elucidates the mechanisms behind a variety of human disorders. It is also useful for evaluating new treatment agents, such as the safety of new vaccines. The zebrafish model is a bridge between in vitro assays and mammalian in vivo studies. In the last few years, the use of zebrafish (Danio rerio) as well-established animal model system for nanoparticle toxicity assessment has expanded dramatically. The zebrafish holds the chance of making contributions to a number of tiers of the drug improvement process, such as target identity, disease modelling, lead finding, and toxicity. This review summarizes that Zebra fish have been used as potential experimental models in a number of research.
KEYWORDS
Zebrafish, Animal Model, Human Safety, Toxicological Research, Vaccine Safety, Nano Particle Toxicity, In Vitro Screens
Cite This Paper in IEEE or APA Citation Styles
(a). IEEE Format:
[1] Riya K. Mehta , Yash D. Dudhwala , Nandini M. Gamit , Vipul G. Gajera , Ketan V. Shah , "Zebra Fish: A Prospective Experimental Model," Advances in Pharmacology and Pharmacy, Vol. 13, No. 4, pp. 662 - 673, 2025. DOI: 10.13189/app.2025.130416.
(b). APA Format:
Riya K. Mehta , Yash D. Dudhwala , Nandini M. Gamit , Vipul G. Gajera , Ketan V. Shah (2025). Zebra Fish: A Prospective Experimental Model. Advances in Pharmacology and Pharmacy, 13(4), 662 - 673. DOI: 10.13189/app.2025.130416.