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Universal Journal of Chemistry(CEASE PUBLICATION) Vol. 2(4), pp. 53 - 58
DOI: 10.13189/ujc.2014.020401
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Synthesis and Antimicrobial Activities of New N-Glycoside from Phenyl Pyrazole Derivatives

Atef M. Amer , Amira A. Ghoneim ^*, Mohamed H. Sherif , Wael Farouk
Chemistry Department, Faculty of Science, Zagazig University, Zagazig, Egypt

ABSTRACT

A series of novel N-glycoside phenyl pyrazole derivatives 5-9 were synthesized by initial reactions of Acetophenone semicarbazone with phosphorus oxychloride to give 3-phenyl-1H-pyrazole-4-carbaldehyde 2 which was reacted with glucose to give N-glycoside. Some of the synthesized compounds have been screened as antibacterial and antifungal. The structures of the synthesized compounds have been deduced from their elemental analysis and spectral (IR, ¹H-NMR) data.

KEYWORDS
Phenylpyrazole, Acetobromoglucose, Antibacterial, Antifungal

Cite This Paper in IEEE or APA Citation Styles
(a). IEEE Format:
[1] Atef M. Amer , Amira A. Ghoneim , Mohamed H. Sherif , Wael Farouk , "Synthesis and Antimicrobial Activities of New N-Glycoside from Phenyl Pyrazole Derivatives," Universal Journal of Chemistry(CEASE PUBLICATION), Vol. 2, No. 4, pp. 53 - 58, 2014. DOI: 10.13189/ujc.2014.020401.

(b). APA Format:
Atef M. Amer , Amira A. Ghoneim , Mohamed H. Sherif , Wael Farouk (2014). Synthesis and Antimicrobial Activities of New N-Glycoside from Phenyl Pyrazole Derivatives. Universal Journal of Chemistry(CEASE PUBLICATION), 2(4), 53 - 58. DOI: 10.13189/ujc.2014.020401.