Journals Information
Universal Journal of Microbiology Research(CEASE PUBLICATION) Vol. 4(2), pp. 49 - 54
DOI: 10.13189/ujmr.2016.040203
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Phytochemical and Antimicrobial Screening of Cola gigantea Leaves, Stem and Bark
Adindu Chukwuemeka Steve 1, Odili Lucy Chidinma 1, Nwagu Ezinne Emmanuella 1, Agu Kingsley Chukwuebuka 1,*, Awah Nsikak Sunday 1, Okeke Benjamin Chidi 2, Orjionwe Rita Nchedo 3
1 Department of Applied Biochemistry, Nnamdi Azikiwe University, PMB 5025, Awka, Nigeria
2 Department of Applied Microbiology and Brewing, Nnamdi Azikiwe University, PMB 5025, Awka, Nigeria
3 GeoSearch Inc. Calgary, Canada
ABSTRACT
Phytochemical and antimicrobial analysis were carried out on the leaves, stem and bark extracts of Cola gigantea. The Phytochemicals present in the plant were Flavonoid, Tannins, Alkaloid, Cardiac glycoside, Steroids, Terpenoids and phenol. Flavonoid, Alkaloid and steroids were present in high amount in the plant than the other phytochemicals. For antimicrobial screening, the well-in-agar diffusion method was employed and the various zones of inhibition produced by the extract of the various plant parts on Escherichia coli, Bacillus subtilis, Staphylococcus aureus and Candida albicans were observed and recorded in millimeters (mm). The leaves of the plant had highest antimicrobial activities on Escherichia coli, Bacillus subtilis and Staphylococcus aureus, while the stem had highest antimicrobial activity on Candida albicans. The observed antimicrobial activity of the extract suggests its potential use in the treatment of diseases produced by the various test pathogenic microorganisms.
KEYWORDS
Phytochemistry, Antimicrobial Screening, Cola gigantea, Leaf, Stem, Bark
Cite This Paper in IEEE or APA Citation Styles
(a). IEEE Format:
[1] Adindu Chukwuemeka Steve , Odili Lucy Chidinma , Nwagu Ezinne Emmanuella , Agu Kingsley Chukwuebuka , Awah Nsikak Sunday , Okeke Benjamin Chidi , Orjionwe Rita Nchedo , "Phytochemical and Antimicrobial Screening of Cola gigantea Leaves, Stem and Bark," Universal Journal of Microbiology Research(CEASE PUBLICATION), Vol. 4, No. 2, pp. 49 - 54, 2016. DOI: 10.13189/ujmr.2016.040203.
(b). APA Format:
Adindu Chukwuemeka Steve , Odili Lucy Chidinma , Nwagu Ezinne Emmanuella , Agu Kingsley Chukwuebuka , Awah Nsikak Sunday , Okeke Benjamin Chidi , Orjionwe Rita Nchedo (2016). Phytochemical and Antimicrobial Screening of Cola gigantea Leaves, Stem and Bark. Universal Journal of Microbiology Research(CEASE PUBLICATION), 4(2), 49 - 54. DOI: 10.13189/ujmr.2016.040203.