Journals Information
Advances in Pharmacology and Pharmacy Vol. 1(2), pp. 37 - 41
DOI: 10.13189/app.2013.010201
Reprint (PDF) (225Kb)
Analysis of Anti-Xa Concentrations in Patients on Treatment Dose Enoxaparin: A Retrospective Chart Review
Lauren Levine1, Nicole Pallme1, Erik Angelotti1, Dane Shiltz2,*
1 Butler University College of Pharmacy and Health Sciences, Indianapolis, 46208, Indiana, United States
2 Indiana University Health Methodist Hospital, Indianapolis, 46202, Indiana, United States
ABSTRACT
The purpose of this retrospective chart review was to determine the correlation between full weight-based enoxaparin use and the frequency of anti-Xa concentrations within the defined therapeutic range; to ascertain if anti-Xa monitoring is being appropriately ordered in relation to the timing of enoxaparin dose (after 3 consistent therapeutic doses and 3-5 hours post-dose); to establish if the evidence-based recommended dose adjustment protocol that was studied in the pediatric population was utilized; and if this yielded anti-Xa concentrations within the target range (0.6 鈥� 1.1 IU/mL) for an adult population. The data may suggest a lack of correlation between BMI and whether or not the anti-Xa concentration is within the therapeutic range. Further prospective studies are needed to confirm this finding, and to determine the utility of the available dose adjustment nomogram.
KEYWORDS
Enoxaparin, Anti-Xa, Anticoagulation
Cite This Paper in IEEE or APA Citation Styles
(a). IEEE Format:
[1] Lauren Levine , Nicole Pallme , Erik Angelotti , Dane Shiltz , "Analysis of Anti-Xa Concentrations in Patients on Treatment Dose Enoxaparin: A Retrospective Chart Review," Advances in Pharmacology and Pharmacy, Vol. 1, No. 2, pp. 37 - 41, 2013. DOI: 10.13189/app.2013.010201.
(b). APA Format:
Lauren Levine , Nicole Pallme , Erik Angelotti , Dane Shiltz (2013). Analysis of Anti-Xa Concentrations in Patients on Treatment Dose Enoxaparin: A Retrospective Chart Review. Advances in Pharmacology and Pharmacy, 1(2), 37 - 41. DOI: 10.13189/app.2013.010201.