Journals Information
International Journal of Cardiovascular and Cerebrovascular Disease(CEASE PUBLICATION) Vol. 4(3), pp. 27 - 34
DOI: 10.13189/ijccd.2016.040301
Reprint (PDF) (604Kb)
Left Ventricular Diastolic Dysfunction and Obesity: A Systematic Review and Meta-analysis of Echocardiographic Studies
Luo Liyun , Li Songbiao *, Wang Chengshan , Lin Xiufang
Department of Cardiology, the Fifth Affiliated Hospital of Sun Yat-Sen University, China
ABSTRACT
Objective: Left ventricular diastolic dysfunction is a common cardiac condition in obese individuals. An updated review and meta-analysis focusing on this issue is lacking, we analyzed the literatures in order to conduct comprehensive information on the left ventricular diastolic function changes, as assessed by echocardiography, associated to obesity. Methods: A literature search using the keywords 'left ventricular diastolic dysfunction', 'diastolic dysfunction', 'obesity', 'obese' 'body mass index' and 'echocardiography' was performed in order to identify relevant papers. Full articles published in English in peer-reviewed journals in past 20 years reporting studies in adult obese individuals were considered. Results: A total of 11 studies including 5171 participants (2764 adults are obese patients) were considered. Obesity was defined as a BMI of 鈮�30kg/m2.Meta-analysis of selected 11 studies (2764 obesity subjects and 2407 normal weight) found that there is no difference of peak late diastolic mitral flow velocity (A) and deceleration time of early diastolic flow wave (DT) between the two groups, while other related parameters such as peak late diastolic mitral flow velocity (A) and E/A ratio, isovolumic relaxation time (IVRT), early diastolic myocardial velocities (E') and E/E' ratio are significant different between obese individuals and non-obese controls, the values of A, IVRT and E/E' were higher in obesity group compared with that of in control group, while the values of E/A ratio and E' were lower in obesity group. Conclusions: Our study shows that left ventricular diastolic dysfunction is present in obese population, Body mass index was found as a significant predictor for DD.
KEYWORDS
Left Ventricular Diastolic Dysfunction, Body Mass Index, Obese, Echocardiography
Cite This Paper in IEEE or APA Citation Styles
(a). IEEE Format:
[1] Luo Liyun , Li Songbiao , Wang Chengshan , Lin Xiufang , "Left Ventricular Diastolic Dysfunction and Obesity: A Systematic Review and Meta-analysis of Echocardiographic Studies," International Journal of Cardiovascular and Cerebrovascular Disease(CEASE PUBLICATION), Vol. 4, No. 3, pp. 27 - 34, 2016. DOI: 10.13189/ijccd.2016.040301.
(b). APA Format:
Luo Liyun , Li Songbiao , Wang Chengshan , Lin Xiufang (2016). Left Ventricular Diastolic Dysfunction and Obesity: A Systematic Review and Meta-analysis of Echocardiographic Studies. International Journal of Cardiovascular and Cerebrovascular Disease(CEASE PUBLICATION), 4(3), 27 - 34. DOI: 10.13189/ijccd.2016.040301.