Journals Information
Advances in Pharmacology and Pharmacy Vol. 5(1), pp. 12 - 19
DOI: 10.13189/app.2017.050102
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Erythrosine Incorporated Fast-Dissolving Patches for Dental Plaque Disclosing
Prasopchai Tonglairoum 1, Theerasak Rojanarata 1, Tanasait Ngawhirunpat 1, Prasert Akkaramongkolporn 1, Ruchadaporn Kaomongkolgit 2, Praneet Opanasopit 1,*
1 Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, Thailand
2 Department of Oral Diagnosis, Faculty of Dentistry, Naresuan University, Phitsanulok, Thailand
ABSTRACT
The aim of this study was to develop erythrosine-loaded electrospun polyvinyl pyrrolidone/ hydroxypropyl-尾-cyclodextrin (PVP/HP尾CD) fiber patches for plaque disclosing. The fiber patches had been fabricated via electrospinning process and were characterized using scanning electron microscope (SEM), Fourier transform infrared spectrophotometry (FT-IR), differential scanning calorimeter (DSC) and powder X-ray diffractometry (PXRD). The fiber patches were then further evaluated for wetting and integration abilities, mechanical properties, loading efficiency, loading capacity and release characteristic. These erythrosine-loaded fiber patches exhibited excellent wetting and disintegration properties and prompt released the erythrosine form the patches after contacted with saliva. These erythrosine-loaded fiber patches could be exploited as a plaque-disclosing material. However, further in vivo studies are needed for the application.
KEYWORDS
Erythrosine, PVP/HP尾CD, Plaque, Disclosing Agent, Oral Patches
Cite This Paper in IEEE or APA Citation Styles
(a). IEEE Format:
[1] Prasopchai Tonglairoum , Theerasak Rojanarata , Tanasait Ngawhirunpat , Prasert Akkaramongkolporn , Ruchadaporn Kaomongkolgit , Praneet Opanasopit , "Erythrosine Incorporated Fast-Dissolving Patches for Dental Plaque Disclosing," Advances in Pharmacology and Pharmacy, Vol. 5, No. 1, pp. 12 - 19, 2017. DOI: 10.13189/app.2017.050102.
(b). APA Format:
Prasopchai Tonglairoum , Theerasak Rojanarata , Tanasait Ngawhirunpat , Prasert Akkaramongkolporn , Ruchadaporn Kaomongkolgit , Praneet Opanasopit (2017). Erythrosine Incorporated Fast-Dissolving Patches for Dental Plaque Disclosing. Advances in Pharmacology and Pharmacy, 5(1), 12 - 19. DOI: 10.13189/app.2017.050102.