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Advances in Pharmacology and Pharmacy Vol. 5(3), pp. 31 - 43
DOI: 10.13189/app.2017.050301
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Nanoparticles as a Platform for Antimicrobial Drug Delivery


Satish Patel 1, Deependra Singh 1, Shikha Srivastava 1, Manju Singh 1, Kamal Shah 2, Durgesh Nandini Chauahn 3, Nagendra S Chauhan 4,*
1 University Institute of Pharmacy, Pt. Ravishankar Shukla University, India
2 Institute of Pharmaceutical Research, GLA University, Mathura, India
3 Columbia Institute of Pharmacy, Raipur (C.G.), India
4 Drug Testing Laboratory and Research Center (AYUSH Lab), India

ABSTRACT

The hasty developments in nanotechnology will have intense impact on various areas of therapeutic applications like drugs and bioactive delivery, tissue engineering, and other application. This review mainly emphasized on the nanoparticle systems for delivery of antimicrobial drug. Various antimicrobial agents have been used to kill or inhibit the growth of microbes such as bacteria, fungi and viruses. As the pharmacological actions of these drugs have been well established, feeble delivery and degradation could lead to insufficient therapeutic index and cause side effects. Nanoparticles have many advantages like small and controllable size, large surface area to mass ratio, and functionalizable structure. These properties make the nanoparticles, a suitable delivery system of antimicrobials. Along with this, it also overcomes the limitations intra-additional antimicrobial therapeutics. In last few years, development and fabrication of antimicrobial agent in nanoparticle systems has evolved as an innovative and promising alternative that increases therapeutic effectiveness and overcoming the undesirable side effects. In this chapter, we focused on the current progress and challenges in producing nanoparticle system for antimicrobial drugs delivery for the treatment of microbial diseases.

KEYWORDS
Nanoparticles, Nanotechnology, Antimicrobial Drug Delivery

Cite This Paper in IEEE or APA Citation Styles
(a). IEEE Format:
[1] Satish Patel , Deependra Singh , Shikha Srivastava , Manju Singh , Kamal Shah , Durgesh Nandini Chauahn , Nagendra S Chauhan , "Nanoparticles as a Platform for Antimicrobial Drug Delivery," Advances in Pharmacology and Pharmacy, Vol. 5, No. 3, pp. 31 - 43, 2017. DOI: 10.13189/app.2017.050301.

(b). APA Format:
Satish Patel , Deependra Singh , Shikha Srivastava , Manju Singh , Kamal Shah , Durgesh Nandini Chauahn , Nagendra S Chauhan (2017). Nanoparticles as a Platform for Antimicrobial Drug Delivery. Advances in Pharmacology and Pharmacy, 5(3), 31 - 43. DOI: 10.13189/app.2017.050301.