Journals Information
Advances in Pharmacology and Pharmacy Vol. 6(2), pp. 50 - 56
DOI: 10.13189/app.2018.060203
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Effect of Hydroalcoholic Extract of Capparis decidua (Forssk.) Edgew on Sexual Behavior of Male Rats
Prashant Kumar Dhakad 1,*, Pramod Kumar Sharma 1, Sokindra Kumar 2
1 Department of Pharmacy, Galgotias University, Greater Noida, 201310, Uttar Pradesh, India
2 R.V. Northland Institute (RVNI), Chithera, Dadri, Greater Noida-II, 203207, Uttar Pradesh, India
ABSTRACT
Capparis decidua has traditionally been recommended as an aphrodisiac agent. Although, it's medicinal use has not been scientifically proved. The present study therefore evaluated the effects of hydroalcoholic extract of C. decidua roots, stem and leaf on sexual behavior in normal male rats. The hydroalcoholic extract of C. decidua was administered (100 mg/kg, 200mg/kg) to different groups of male wistar rats for 28 days. The female rats were brought in estrous phase before the mating in each group of male rats. Standard group was administered sildenafil citrate at 5mg/kg orally for 28 days. Control group was administered only distilled water. All the experimental groups i.e C. decidua 100mg/kg, 200 mg/kg, per se group (only C. decidua 200 mg/kg), standard group(sildenafil citrate 5mg/kg) were compared with the control group for parameters evaluated for sexual behavior study. C. decidua at 100mg/kg, 200 mg/kg, and per se treated groups produced significant arousal of sexual activity in male rats. They significantly increased the frequencies of mount, intromission frequency. The mount latency and intromission latency were significantly reduced but ejaculation latency was prolonged significantly. The results indicated that hydroalcoholic extract of C. decidua enhanced sexual behaviour in male rats. The enhanced sexual behavior in male rats at the doses of 100 and 200 mg/kg body weight may be due to the presence of phytochemicals like alkaloids, saponins, flavonoids as these phytochemicals has role in increasing sexual strength, androgen enhancing, and antioxidant activity.
KEYWORDS
Aphrodisiac, Capparis decidua, Sexual Behavior, Sildenafil Citrate, Phytochemicals
Cite This Paper in IEEE or APA Citation Styles
(a). IEEE Format:
[1] Prashant Kumar Dhakad , Pramod Kumar Sharma , Sokindra Kumar , "Effect of Hydroalcoholic Extract of Capparis decidua (Forssk.) Edgew on Sexual Behavior of Male Rats," Advances in Pharmacology and Pharmacy, Vol. 6, No. 2, pp. 50 - 56, 2018. DOI: 10.13189/app.2018.060203.
(b). APA Format:
Prashant Kumar Dhakad , Pramod Kumar Sharma , Sokindra Kumar (2018). Effect of Hydroalcoholic Extract of Capparis decidua (Forssk.) Edgew on Sexual Behavior of Male Rats. Advances in Pharmacology and Pharmacy, 6(2), 50 - 56. DOI: 10.13189/app.2018.060203.